NYeC is eager to release our 2020 Year-End Report. Despite the year’s relentless challenges—many that continue today, NYeC and the SHIN-NY delivered critical support to the healthcare and public health community, and advanced health information exchange throughout New York State in 2020. This report highlights much of that great work. We look forward to a new year of success and collaboration with New York State, our partners, and all of our stakeholders in consistent pursuit of our vision: a dramatically transformed healthcare system where health information exchange is universally used as a tool to make lives better.